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« Will a ‘Regular’ Flu Shot Protect One Against Bird Flu? | Main | Risk of Stroke from Air Pollution? »
Friday
Nov042005

Surgery to Protect Against Infection?

This may be a first.  A surgical procedure is able to confer protection against a life-threatening infection.  Any guesses? 
The answer is that circumcision reduces the rate of HIV infection in African men by 60%, according to a recently-reported study.  What’s encouraging about this report is that it was a prospective study, i.e. it wasn’t just a survey about infections in groups of circumcised and non-circumcised men.
Over 3,000 uncircumcised men in Johannesburg, aged 18-24, allocated at random to be circumcised or not.   After 18 months’ follow-up, it was found that 20 of the circumcised men had developed HIV infections, compared with 49 infections in the non-circumcised group. 
This excellent result is roughly equivalent to the results to be expected from an effective vaccine.  Now all we want is a surgical procedure to protect us against bird flu.  Suggestions, anyone?


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