A New Test for Lung Cancer

There are over 150,000 lung cancer deaths in the USA each year. Te problem is that it’s difficult to detect early, when it’s most amenable to treatment, so the mortality rate remains high. Obviously, anything that would help an early diagnose would be extremely valuable.

A new test has now been reported that involves measuring a protein called tNOX in the blood. Normal cells produce the NOX enzyme only when they divide in response to growth hormone, while cancer cells produce a form of NOX – called tNOX – continuously. In preliminary tests in healthy non-smokers, apparently healthy smokers, and patients with lung cancer, the researchers from Purdue University and Mount Sinai, NY, showed hopeful results. There were no positive results in 140 non-smokers, 99% positives in lung cancer patients, and 12% positive in 175 apparently healthy smokers; 12% is roughly the incidence of positives seen in high resolution lung scanning techniques. These findings suggest the test could be used in smokers to detect those who need further – and more expensive - testing, such as high resolution computerized tomography (CT).

This test, if the findings are confirmed, is clearly a major advance. However, everyone stopping smoking would be an even greater advance, and maybe even render such tests obsolete before they’re available.

Comments

[danishimonking]

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Jay