Postmenopausal HRT May Increase Risk of GERD

A study in the Archives of Internal Medicine reports that postmenopausal women who take hormone replacement therapy (HRT) may be at increased risk for gastroesophageal reflux disease (GERD).

Boston researchers used data from the Nurses' Health Study, which includes over 50,000 women. They identified some 12,000 postmenopausal women who reported symptoms of GERD occurring at least weekly; their health data were compared with those from about 40,000 controls without symptoms.
After adjustment were made for body mass index, age, and other factors that might influence the findings, it was seen that the likelihood of developing GERD was significantly increased with past hormone use, current use of estrogen only, and current use of estrogen plus progesterone, compared with ‘never-use’ women. The hormone users were approximated 1½-times as likely to develop GERD. Selective estrogen receptor modulators, such as tamoxifen and raloxifene, which act directly with estrogen receptors in the body, were also associated with GERD.
One must agree with the researchers, who conclude that women seeking treatment for menopause-related symptoms, as well as breast cancer and osteoporosis prevention, "should be counseled about the potential for symptoms of GERD associated with hormone therapies." Fortunately, the symptoms of GERD usually respond well to medical treatment.

Comments

[diabetes man]

all is about hormone production....... very great information related between menopouse and severe gerd disease