What’s the Risk of Kidney Disease in Overweight Hypertensives?

End-stage renal disease (ESRD) is a serious condition that can result fro a combination of high blood pressure and being obese. It usually means regular dialysis or a kidney transplant to keep alive, so, not surprisingly, researchers have examined the circumstances leading to ESRD more carefully.

A publication in the American Journal of Kidney Diseases describes this Norwegian study, and its results. The intent was to better characterize the risk associated with prehypertension (blood pressure of 120-139/80-89 mm Hg) and overweight (body mass index or BMI of 25-30) vs. obesity (BMI over 30).

Data came from almost 75,000 participants in a large study in Nord-Trondelag, whose medical information was linked to the Norwegian National Registry; 88% of all inhabitants aged 20 or older were enrolled 20 years ago. Hazard ratios (the relative likelihood of experiencing a particular event in a given period of time) were estimated for treated ESRD and death due to chronic kidney disease for different blood pressure and BMI categories.

The risk (or hazard ratio) for ESRD or chronic renal death associated with body weight started to increase from a BMI of 25.0 upwards. In participants with a blood pressure below 120/80 mm Hg the risk didn’t increase with increased BMI. In the prehypertensive subjects, the risk of ESRD or renal death was only increased when the BMI was greater than 30, i.e. with an obese rather than an overweight classification.

Maybe this is good news if you’re only overweight and prehypertensive. But remember both conditions are early stages of much worse things, and should serve as warnings to do something about your health. Exercise and sensible eating are the best ways to keep you risk of kidney disease, as well as of a lot of other diseases, as small as possible.

Comments

[e-uroloji]

tnx for usefull infromation.